The opioid crisis and the flood of other drugs has reached epidemic proportion in many of our tribal communities across the nation. Review emerging drug trends such as Fentanyl, Fentanyl laced pills, heroin, cocaine, methamphetamines, synthetic cannabinoids, and other chemicals. Discuss specific challenges associated with vaping, butane hash oil, cannabis edibles. Explore the issues these “new drug delivery systems” have caused many states and tribal communities. Consider how particular drugs are designed and why the designs of these drugs are so popular. Review the stages of use, addiction, withdrawal symptoms, and the health and life-threatening dangers posed from the use of drugs. Discuss common delivery systems and observe examples of emerging drugs in various forms. Recognize the signs and symptoms of drug usage, as well as how Naloxone/Narcan works in cases of opioid overdoses.